Pathogenicity of Highly Pathogenic Avian Influenza Virus (H5N1) in Adult Mute Swans

نویسندگان

  • Donata Kalthoff
  • Angele Breithaupt
  • Jens P. Teifke
  • Anja Globig
  • Timm Harder
  • Thomas C. Mettenleiter
  • Martin Beer
چکیده

Adult, healthy mute swans were experimentally infected with highly pathogenic avian influenza virus A/Cygnus cygnus/Germany/R65/2006 subtype H5N1. Immunologically naive birds died, whereas animals with preexisting, naturally acquired avian influenza virus-specific antibodies became infected asymptomatically and shed virus. Adult mute swans are highly susceptible, excrete virus, and can be clinically protected by preexposure immunity.

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عنوان ژورنال:
  • Emerging Infectious Diseases

دوره 14  شماره 

صفحات  -

تاریخ انتشار 2008